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Liz Plosser

Liz Baker Plosser 

Effects of Estradiol Withdrawal on Mood in Women With Past Perimenopausal Depression: A Randomized Clinical Trial.

Efficacy of Transdermal Estradiol and Micronized Progesterone in the Prevention of Depressive Symptoms in the Menopause Transition: A Randomized Clinical Trial.

Menopausal Hormone Therapy and Type 2 Diabetes Prevention: Evidence, Mechanisms, and Clinical Implications.

Enhanced Neuroactivation during Verbal Memory Processing in Postmenopausal Women Receiving Short Term Hormone Therapy

Sharon Malone, MD

Dr. Sharon D. Malone headshot.

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Estrogen therapy supports brain health, bone strength, metabolism, sleep, and mood during perimenopause and menopause, offering evidence-based longevity benefits for women.

Estrogen Therapy: Biohacking for Women

Estrogen: The Powerful Longevity Biohack Hiding in Plain Sight

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Anne Fulenwider

Anne Fulenwider headshot.

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Reset your health this year with expert menopause tips on sleep, stress, sex, skin, hair, and connection. Start thriving in midlife with Alloy’s guide.

Your Midlife Health Reset: Thrive Through Menopause in 2026

Alloy’s 2026 Midlife Thrive Guide 

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Alloy Staff

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Corinne Menn, D.O.

Updated Dr. Menn Headshot

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Struggling with digestive issues during menopause? Learn what helps to relieve bloating, reflux, and more.

What Helps With Digestive Issues During Menopause?

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Dr. Corinne Menn headshot on green square graphic.

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Skin changes like dryness, rosacea, and eczema are common in perimenopause. Learn how hormone shifts affect your skin—and what treatments really help.

How Perimenopause Affects Your Skin: Dryness, Rosacea & Eczema

Perimenopause Skin Changes Explained: Understanding Menopause’s Impact on Your Skin

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Kudzai Dombo, MD

Kudzai Dombo

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Perimenopause isn’t one story—it’s thousands. Discover real voices, expert advice, and personalized care options for your unique experience with Alloy.

Perimenopause Symptoms Are Different for Every Woman | Alloy

Perimenopause Isn’t One Story: Here’s Why Every Voice Matters

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Sheryl Kraft

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The microbiome in autoimmune diseases.

Females Are More Anxious Than Males: a Metacognitive Perspective

Primary osteoporosis in postmenopausal women

The Prevalence of Autoimmune Disorders in Women: A Narrative Review

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Women's health worries like heart disease, breast cancer, osteoporosis, depression, and autoimmune diseases explained with symptoms, risks, and prevention tips.

Breast Cancer FAQs | Alloy

What Worries Women Most About Their Health — and Why

Age of menopause and impact of climacteric symptoms by geographical region.

The menopause and obesity.

Effects of Smoking on Menopausal Age: Results From the Korea National Health and Nutrition Examination Survey, 2007 to 2012

Eunice Kennedy Shriver National Institute of Child Health and Human Development - NICHD

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The average age for menopause is 51, but symptoms often start earlier. Learn the timeline of perimenopause and what to expect as you age.

What is the Average Age for Menopause to Start? Alloy Health

What Is the Average Age for Menopause to Start?

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Blog - Start Weight Care Consult

Start Your Weight Care Consult

Monica Molenaar

Dr. Michelle Montville

Michelle Montville

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See how combining MHT with GLP-1s like Semaglutide, Tirzepatide, & Compounded Liraglutide boosts weight loss, improves health, & supports women’s wellness.


GLP-1 and Menopausal Hormone Therapy: A Powerful Combination

Why GLP-1s and MHT Are a Beneficial Combination 

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Blog - Get Minoxidil

Get Minoxidil $33

Vivian Manning-Schaffel

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Effect of a nutritional supplement on hair loss in women.

Treatment of female pattern hair loss with oral antiandrogens.

A randomized, double-blind controlled study of the efficacy and safety of topical solution of 0.25% finasteride admixed with 3% minoxidil vs. 3% minoxidil solution in the treatment of male androgenetic alopecia.

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Concerned about thinning hair? Find out if menopausal hair loss is permanent and explore the medical treatments and lifestyle changes that can help.

Is Menopausal Hair Loss Permanent? What You Need to Know

Is Menopausal Hair Loss Permanent?

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Sharon D. Malone, MD

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All topical estrogens work whether they are administered as a cream, a vaginal pill, a suppository, or a ring. Alloy chose to offer the cream. Learn why.

Topical Estrogen: Why Use Cream? | Alloy

Topical Estrogen: Why Use Cream?

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Lephart, E. D., & Naftolin, F. (2020). Menopause and the Skin: Old Favorites and New Innovations in Cosmeceuticals for Estrogen-Deficient Skin. Dermatology and Therapy, 11(1), 53–69

Stevenson, S., & Thornton, J. (2007). Effect of estrogens on skin aging and the potential role of SERMs. Clinical Interventions in Aging, 2(3), 283–297.

Schmidt, J. B., Binder, M., Demschik, G., Bieglmayer, C., & Reiner, A. (1996). Treatment of skin aging with topical estrogens. International Journal of Dermatology, 35(9), 669–674.

Medical (clinical)

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Is it safe?  YES - you can put estriol cream on your face, and you can buy it here.  Studies have confirmed that like local, topical vaginal estradiol, topical facial estriol does not increase systemic serum levels of estrogen

Can you put estriol cream or estrogen gel on your face? 

The Science Behind Putting Estrogen On Your Face

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Signs that perimenopause is ending include increasingly irregular periods, fewer headaches, more stabilized mood, intensified hot flashes, and worsening sleep disturbances. Understanding these changes helps women anticipate the onset of menopause and explore effective treatments such as hormonal therapies and non-hormonal options for symptom relief.

How Long Does Perimenopause Last? Signs That It's Ending - Alloy

How Long Does Perimenopause Last?  4 Signs Perimenopause Is Ending

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Traci Kurtzer

Traci Kurtzer Headshot

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Discover how the Alloy Periodic Table of Menopause combines science, support, and care to help women thrive through midlife and beyond.

The Alloy Periodic Table of Menopause - Vitamins & Treatments

From Chemistry to Care: The Alloy Periodic Table of Menopause

Alloy Periodic Table of Menopause [Top Image]

Shop Skincare Sets - Skincare CLP - External - Lg

View All Skincare

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If you’re going through menopause, you don’t have to suffer. Estradiol is an effective treatment that can help. Learn which formulation is best for you.

Estradiol Patch vs. Pill vs. Spray: What's right for me?

Estradiol Patch vs. Pill vs. Spray: What’s right for me?

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Wondering how long semaglutide takes to work? Learn the timeline, key factors affecting results & tips to maximize effectiveness for weight loss.



How Long Does It Take For Semaglutide to Work? 

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Barbara Brody

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Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date

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Is menopause causing your hair to thin? Explore the most effective hair loss treatments, including topical solutions and hormonal support.

Menopause Hair Loss Treatment: Best Minoxidil Options for Women

Your Best Menopause Hair Loss Treatment Options

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Changing estrogen levels are what contribute to menopause symptoms. Fortunately, we have answers. Learn why estrogen is so important and how to get relief.

Why is Estrogen So Important? | Alloy

Why is Estrogen So Important? 

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GLP-1 medications reduce hunger, improve insulin response, and support weight loss—especially in midlife. Learn how they work and who they help.

How GLP-1s Support Weight Loss & Metabolic Health

How Do GLP-1s Work?

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Dr. Kelly Casperson in black top sitting on a couch

Dr. Kelly Casperson explains essential information about vaginal health during menopause, from common symptoms to effective treatments.

Vaginal Health and Menopause: Expert Guide

Menopause & Your Vagina: Here’s Everything You Need to Know From Dr. Kelly Casperson

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Low-Dose Birth Control Pill

Buy Birth Control Pill -$39

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Opill is a progestin only birth control pill that can be safely used for perimenopausal women who are asymptomatic, in need of birth control and have contraindications to the use of combination oral contraceptives. Progestin only pills are over 90% effective, making them the most effective over the counter contraceptive on the market

Progestin-Only Birth Control Pill & Perimenopause | Alloy

Here’s What You Need to Know About the New OTC Birth Control Pill & Perimenopause

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Dr. Sharon Malone examines the study behind the latest headlines about Menopause, Hormone Replacement Treatment (HRT) and Dementia.

Does HRT Cause Dementia? | Unpacking the Latest Study

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Ad libitum Weekend Recovery Sleep Fails to Prevent Metabolic Dysregulation during a Repeating Pattern of Insufficient Sleep and Weekend Recovery Sleep.

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Do you have trouble getting enough sleep? Learn the effects of sleep deprivation and get tips on how you can get a healthy night's rest.

Is it Really Possible to Catch up on Lost Sleep?

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Estrogen Alone and Joint Symptoms in the Women’s Health Initiative Randomized Trial

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Is the scale moving despite no changes to your diet? Learn the real causes of perimenopausal weight gain and discover expert-backed strategies to take control.

Perimenopause Weight Gain - How to Put a Pause on It | Alloy

Perimenopausal Weight Gain: What You Need to Know

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Rachel Hughes

founder of a concierge gastroenterology and wellness practice

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Gut health and hormones in perimenopause and menopause: discover how estrogen, progesterone, and the gut-brain axis impact bloating, IBS, leaky gut, and mood, plus practical tips for digestive wellness.

How to Restore Gut Microbiome / Health During Menopause | Alloy

Gut Health & Hormones: What Everyone Needs to Know

Dr. Kumkum Sarkar Patel headshot

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There’s good news. Sex after menopause definitely exists. It just might not be as you’ve always remembered it. Dr. Sharon Malone of Alloy explains why.

How to Have Better Sex After Menopause

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Blog - Start an Online Consult

Start an Online Consult

Mayo Clinic. “Perimenopause.

Cleveland Clinic. “Perimenopause.

Johns Hopkins Medicine. “Introduction to Menopause.”

Camila Hirotsu,⁎ Sergio Tufik, and Monica Levy Andersen. “Interactions between sleep, stress, and metabolism: 

Juan Pablo Del Río, María I. Alliende, Natalia Molina, Felipe G. Serrano, Santiago Molina and Pilar Vigil.

Harvard Medical School. “How does exercise reduce stress? Surprising answers to this question and more.” Harvard Health Publishing.

Qi X, Yun C, Pang Y, Qiao J. “The impact of the gut microbiota on the reproductive and metabolic endocrine system.” Gut Microbes. 2021;13(1):1-21. doi:10.1080/19490976.2021.1894070. 

Paweł Milart,corresponding author Ewa Woźniakowska, and Wojciech Wrona. 

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If you are experiencing irregular periods in your 40s, you may be in perimenopause. Find out how you can relieve perimenopause symptoms with Alloy.

What Causes Irregular Periods in Your 40s? Perimenopause

In My 40s & Having Irregular Periods: Am I in Perimenopause?

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Buy Now - Tretinoin

Get Tretnoin Cream $90

Anna Johnson

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Stephanie Culver

Dr. Culver Headshot 2

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Discover the key differences between tretinoin gel and cream, their benefits, side effects, and how to choose the best option for your skin type.

Tretinoin Gel vs Cream: Which is Right for Your Skin? | Alloy

Tretinoin Gel vs Cream: Which is Right for Your Skin?

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