Why Estrogen Belongs in Your Skincare Routine, and Not Just in Your Hormone Therapy
4 minute read
Before we talk about serums or moisturizers, let’s focus on the incredible force that’s been quietly working behind the scenes your entire life: estrogen. Often thought of only in the context of reproduction—from the teenage glow of puberty to the subtle shifts of menopause—this hormone actually powers our bodies in countless essential ways, including how your skin functions with age. Estrogen is at the core of our external selves, because it helps produce collagen, which is the key to maintaining skin thickness, moisture, and elasticity. When collagen is lost, skin becomes thinner, drier, more delicate, and fragile.
How Do We Increase Estrogen in Our Bodies?
If you’re taking MHT (Menopausal Hormone Therapy)… amazing. You already understand the importance of replenishing estrogen as it naturally declines with age, and hopefully you’ve started to feel relief from classic menopause symptoms like hot flashes, night sweats, brain fog, and vaginal dryness. MHT with estrogen also has an overall beneficial impact on skin, but to get more significant improvements in specific areas, low-dose topical estrogens are even better.
One example is using vaginal estrogen to improve dryness and atrophy in menopause. And the great news is that low-dose topical estrogens can also be used on facial skin to help stimulate collagen production, boost hydration, and improve firmness and elasticity.
If you’re not taking MHT? No problem. Topical estriol can still be safely used on its own to significantly support and restore skin health.
Estrogen + Your Skin
As estrogen declines, especially during perimenopause and menopause, your skin starts to show it. Collagen production slows, moisture levels drop, and skin becomes noticeably drier, thinner, less elastic, and more prone to wrinkles and sagging. In fact, by age 50, women may lose as much as 50% of their total collagen compared to their peak. The most effective way to counter this? Give your skin back what it's missing.
According to Dr. Ellen Gendler, board-certified dermatologist and Medical Advisor to Alloy Health: “Adding low-dose topical estrogen to your skincare routine can help combat the adverse effects decreasing estrogen levels have on the skin. Proven safe and effective to use, low-dose topical estrogen is non-systemic and helps keep aging skin strong and supple.”
Our Skincare Is Powered by Estrogen
At Alloy, we understand the connection between estrogen replenishment and overall health. We knew how successful MHT had been for menopausal symptoms, so we took it a step further in 2023. After intensive research, we were the very first company to introduce an anti-aging face cream that included estrogen as an ingredient: our M4 Collagen Builder Rx Face Cream.
And we were right: our original M4 cream was clinically proven to dramatically restore skin health in just 12 weeks*. A 2024 independent study showed:
88% improvement in elasticity
70% improvement in hydration
68% improvement in overall skin health
57% improvement in skin texture
*compared to placebo
Real Women, Real Results
But the most meaningful result for us is how much it’s loved by the actual women who use it. In a 2025 customer survey, almost ALL (92%) of M4 Collagen Builder Rx Face Cream users said they’d recommend it to a friend. The reason? It delivers real, effective results that you can see: smoother, plumper, and more vibrant skin.
Whether you’re taking MHT or not, adding estrogen (and along with it, collagen) to your skincare routine can be a game-changer for skin health. Ready to learn more?
See details about the study and see if M4 Collagen Builder Rx Face Cream is right for you
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