EstriolPeptides
M4 Eye Cream Rx
$90.00
(90 days of treatment)
Our prescription-only eye cream combines 1% estriol with wrinkle-fighting peptides to brighten, tighten, and transform the delicate eye area. The first of its kind–formulated by Alloy to deliver unmatched results for combatting the signs of aging.
Free shipping
Unlimited messaging with a menopause-trained doctor
SAVE 25% WITH THE GLOW & GO SET
Buy all 3 M4 products and save. Learn more
The results are in on M4 Eye Cream Rx
In a 2025 independent clinical study, statistically significant improvements* seen in M4 Eye Cream Rx in a 12-week study include:
25%
improvement in wrinkle reduction
33%
improvement in firmness
40%
improvement in more elasticity
40%
improvement in crepiness on eyelids
M4 Eye Cream Rx can be used with or without MHT because it does not impact blood estrogen levels. *Based on expert assessment
Learn more about M4 Eye Cream Rx
What is it: A prescription-only, estrogen-based anti-aging formulation specifically created for the eye area. Active ingredient estriol increases collagen and elasticity, and peptides reduce fine lines, brighten eye area, and help prevent expression lines. Over 85% of users saw measurable improvement in deep hydration in 12 weeks, and 97% saw a 23% boost in skin hydration.
Full list of ingredients: estriol 1%, palmitoyl pentapeptide-4 0.1%, acetyl hexapeptide-8 0.1%, C12-15 alkyl benzoate, caprylic/capric triglyceride, cetyl alcohol, ethylhexylglycerin, glycerin, glyceryl stearate, hydroxyethyl acrylate/sodium, acryloyldimethyl taurate copolymer, oleic Acid, olea europaea (olive) fruit oil, PEG-100 stearate, phenoxyethanol, dimethicone, polymethylsiloxane, water (aqua), stearic acid, trolamine, tocopheryl (vitamin E) acetate (provides antioxidant protection and helps strengthen the skin barrier).
Who is it for: Women seeking to address signs of aging, as facial wrinkles increase in depth and number significantly after menopause, especially in the perioral and eye areas.
What am I getting: 1 bottle containing 15 grams (3-month supply) of M4 Eye Cream Rx.
How to get it: Prescription required. A menopause-trained doctor will review your medical history to determine if this is the right treatment for you.
Clinically Proven Results in 12 weeks
Firmer, Bouncier-Looking Skin
Reduction in Fine Lines and Wrinkles
The M4 Difference
Our three powerful M4 products (M4 Face Cream Rx, M4 Face Serum Rx, and M4 Eye Cream Rx) boost collagen production, restore hydration, improve elasticity, and support hormonal skin repair, keeping skin resilient, youthful, and balanced.
Each M4 product delivers results on its own—but together, they’re a complete anti-aging powerhouse. Get 25% off when you bundle all three and see what your skin’s been missing. Aging has never looked better.
Did you know?
Facial wrinkles increase in depth and number significantly after menopause, especially in the perioral and eye areas.
What is Estriol?
Estriol is one of three forms of estrogen our bodies naturally produce, until menopause. Once we hit menopause, we lose up to 30% of our dermal collagen in the first five years alone. And it only goes down from there. The solution to losing estrogen is replenishing it, and that's where estriol comes in.
Research shows that topical estriol can address hormonal aging and helps keep skin resilient, youthful, and balanced. Topical estriol stays on the surface of your skin and doesn’t enter your bloodstream, making it safe for everyday use.
The Alloy Promise
Alloy believes that every woman deserves accurate, up-to-date information and the agency to make her own decisions about her health based on facts, not fear.
All of our board-certified physicians follow ACOG and The Menopause Society guidelines and prescribe only FDA-approved, generic medications for the treatment of menopausal symptoms. The safety of our products is our top priority.
