M4 Lift & Renew Rx Eye Cream Standard Squarerx itemrx item
reduces fine lines & brightens the eye area

M4 Lift & Renew Rx Eye Cream

$90.00

(90 days of treatment)

Our prescription-only eye cream combines 1% estriol with wrinkle-fighting peptides to brighten, tighten, and transform the delicate eye area. The first of its kind–formulated by Alloy to deliver unmatched results for combatting the signs of aging.

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    Free shipping

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    Unlimited messaging with a menopause-trained doctor

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SAVE 25% WITH THE GLOW & GO SET

Buy all 3 M4 products and save. Learn more

The results are in on M4 Lift & Renew Rx Eye Cream

In a 2025 independent clinical study, statistically significant improvements* seen in M4 Lift & Renew Rx Eye Cream in a 12-week study include:

arrow up25%
improvement in wrinkle reduction
arrow up33%
improvement in firmness
arrow up40%
improvement in more elasticity
arrow up40%
improvement in crepiness on eyelids

M4 Lift & Renew Rx Eye Cream can be used with or without MHT because it does not impact blood estrogen levels. *Based on expert assessment

Read the full clinical study

Learn more about M4 Lift & Renew Rx Eye Cream

What is it: A prescription-only, estrogen-based anti-aging formulation specifically created for the eye area. Active ingredient estriol increases collagen and elasticity, and peptides reduce fine lines, brighten eye area, and help prevent expression lines. Over 85% of users saw measurable improvement in deep hydration in 12 weeks, and 97% saw a 23% boost in skin hydration.

Full list of ingredients: estriol 1%, palmitoyl pentapeptide-4 0.1%, acetyl hexapeptide-8 0.1%, C12-15 alkyl benzoate, caprylic/capric triglyceride, cetyl alcohol, ethylhexylglycerin, glycerin, glyceryl stearate, hydroxyethyl acrylate/sodium, acryloyldimethyl taurate copolymer, oleic Acid, olea europaea (olive) fruit oil, PEG-100 stearate, phenoxyethanol, dimethicone, polymethylsiloxane, water (aqua), stearic acid, trolamine, tocopheryl (vitamin E) acetate (provides antioxidant protection and helps strengthen the skin barrier).

Who is it for: Women seeking to address signs of aging, as facial wrinkles increase in depth and number significantly after menopause, especially in the perioral and eye areas.

What am I getting: 3-month supply of M4 Lift & Renew Rx Eye Cream (one 15ml bottle).

How to get it: Prescription required. A menopause-trained doctor will review your medical history to determine if this is the right treatment for you.

Clinically Proven Results in 12 weeks
In our 2025 study, 97% experienced a 23% boost in skin hydration immediately after application. Over 85% of users saw measurable improvement in deep hydration.
Firmer, Bouncier-Looking Skin
Skin firmness increased by up to 33%, elasticity improved by up to 40%, and up to 85% of subjects showed an improvement in elasticity, reflecting skin that snaps back with youthful strength.
Reduction in Fine Lines and Wrinkles
Skin around the eyes looked smoother after consistent use, with up to a 25% reduction of wrinkles. Skin texture on the eyelids improved by up to 40%, significantly reducing visible crepiness.

The M4 Difference

Our three powerful M4 products (M4 Collagen Builder Rx Face Cream, M4 Smooth & Firm Rx Priming Serum, and M4 Lift & Renew Rx Eye Cream) boost collagen production, restore hydration, improve elasticity, and support hormonal skin repair, keeping skin resilient, youthful, and balanced.

Each M4 product delivers results on its own—but together, they’re a complete anti-aging powerhouse. Get 25% off when you bundle all three and see what your skin’s been missing. Aging has never looked better.

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Did you know?

Facial wrinkles increase in depth and number significantly after menopause, especially in the perioral and eye areas.

ingredient

What is Estriol?

Estriol is one of three forms of estrogen our bodies naturally produce, until menopause. Once we hit menopause, we lose up to 30% of our dermal collagen in the first five years alone. And it only goes down from there. The solution to losing estrogen is replenishing it, and that's where estriol comes in.

Research shows that topical estriol can address hormonal aging and helps keep skin resilient, youthful, and balanced. Topical estriol stays on the surface of your skin and doesn’t enter your bloodstream, making it safe for everyday use.

Read the study

How it works

1.

Personalize Your Treatment

Fill out a quick intake to share your symptoms and goals

2.

Match With a Doctor

Connect with a board-certified doctor in just hours

3.

Easily Manage Your Plan

Receive a treatment plan tailored to your body, your symptoms, your life

4.

Care Delivered to Your Door

Get your prescriptions sent right to your doorstep

Frequently asked questions

  • Is M4 Lift & Renew Rx Eye Cream right for me?+

    Most women are good candidates. A doctor will confirm after a quick assessment.

  • Can I use this with hormone therapy?+

    Yes—M4 Lift & Renew Rx Eye Cream is non-systemic and safe with MHT and vaginal estrogen.

  • Do I need progesterone?+

    No—because M4 is not systemic, progesterone is not required.

  • Where is Alloy available?+

    All 50 U.S. states and D.C. (Global users can still access our content & resources.)

What our customers are saying:

The Alloy Promise

Alloy believes that every woman deserves accurate, up-to-date information and the agency to make her own decisions about her health based on facts, not fear.


All of our board-certified physicians follow ACOG and The Menopause Society guidelines and prescribe only FDA-approved, generic medications for the treatment of menopausal symptoms. The safety of our products is our top priority.


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