When and why might hormone therapy be discussed as part of frozen shoulder management in women?

Hormone therapy (HT), specifically estrogen therapy, is increasingly discussed as part of frozen shoulder management in women, especially during perimenopause and menopause. Here at Alloy, we recognize that frozen shoulder is much more common in midlife women, and research is showing a strong link between declining estrogen levels and increased inflammation in the shoulder joint.

Why is hormone therapy relevant?

Estrogen has anti-inflammatory effects and helps keep joints lubricated and healthy. When estrogen declines during menopause, the risk of inflammatory conditions like frozen shoulder rises.
Studies have shown that women on estrogen therapy have a significantly lower incidence of frozen shoulder compared to those who are not.
Estrogen loss not only affects joint pain but also increases the risk of osteoporosis and muscle loss, making overall musculoskeletal health a key concern in menopause.

When might hormone therapy be discussed?

If you are a midlife woman experiencing sudden, severe shoulder pain and stiffness (classic signs of frozen shoulder), your healthcare provider may discuss hormone therapy as part of a comprehensive management plan.
HT may be considered especially if you have other menopausal symptoms or risk factors for bone and muscle loss.
The decision to start hormone therapy is individualized, based on your symptoms, health history, and preferences.

What else is important in management?

Early movement and physical therapy are crucial—resting the shoulder can make things worse.
In some cases, steroid injections or regenerative treatments like platelet-rich plasma may be used if pain is severe.
Hormone therapy is one tool among several, but it can play a protective and restorative role for joint health in menopausal women.

For a deeper dive, check out these resources:

Watch Dr. Vonda Wright explain the connection between estrogen, inflammation, and frozen shoulder, and how hormone therapy fits into the treatment plan in this YouTube chapter: Frozen Shoulder & Musculoskeletal Symptoms.
Learn more about the science and practical steps in our blog: How to Stay Strong in Menopause & Beyond.
Explore Alloy’s range of hormone therapy options, including estradiol pills, patches, and gels.

If you’re considering hormone therapy for frozen shoulder or other menopause symptoms, you can take our online assessment to find the best treatment plan for you.

At Alloy, we’re here to help you feel strong, supported, and informed through every stage of menopause.

This answer was created using the following resources: