How should the dose and regimen of menopausal hormone therapy be determined?

The dose and regimen of menopausal hormone therapy (MHT) should be individualized to each person’s needs, symptoms, and health profile. Here at Alloy, our menopause-trained doctors follow evidence-based guidelines and work closely with you to find the best solution. Here’s how the process works:

  • The best dose is the one that effectively treats your symptoms while minimizing side effects. There is no “one-size-fits-all” dose—some people feel great on a low dose, while others may need a higher dose for relief.
  • Your doctor will consider your age, how long it’s been since your last period, your specific symptoms, your medical history, and your personal preferences.
  • Alloy offers a range of FDA-approved, bioidentical hormone options, including estradiol pills, patches, gels, sprays, and vaginal creams. Each has different dosing options and can be tailored to your needs. For example, the estradiol patch comes in five different strengths.
  • Dose adjustments are based on your symptom response, not on blood tests. Your doctor will monitor how you feel and adjust your regimen as needed.
  • If you have a uterus, you’ll also be prescribed progesterone to protect your uterine lining.
  • The choice between oral and transdermal (patch, gel, spray) forms may depend on your health risks, convenience, and cost. For example, transdermal options are often preferred if you have higher risk factors for blood clots.

For a deeper dive into how dosing is personalized, check out this chapter from our YouTube webinar with Dr. Corinne Menn: Individualizing Hormone Therapy Dosing.

You can also learn more about our approach and explore our full range of MHT products on our solutions page.

If you’re ready to get started, complete our online assessment and a menopause-trained doctor will review your history and help you find the right dose and regimen for you!


This answer was created using the following resources: