Your Skin Deserves Prescription-Strength Care

Alloy's M4 skincare is the first estriol-powered formula clinically proven to rebuild collagen, restore elasticity, and visibly reduce wrinkles in just 12 weeks.

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Featured in Oprah's O-wards

Menopause-Expert Doctors

Simple Intake Form

HSA and FSA Eligible

Monica Before & After

Clinically Proven M4 Skincare

Alloy became the first company to offer skincare with estriol—and independent tests showed significant, measurable results. In just 12 weeks, women using M4 creams saw visibly firmer, smoother, more radiant skin.

23%

Increase in under-eye hydration

UP TO86%

Boost in skin elasticity and bounce

UP TO25%

Reduction in wrinkles around eyes

68%

Improvement in overall skin health

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How to Get Alloy Skincare

Prescription skincare, made effortless.

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Alloy’s Complete Prescription Skincare

BEST SELLERM4 Face Cream Rx

M4 Face Cream Rx

Estriol

$150.00

90 days of treatment, $50 per month

Restore elasticity, hydrate deeply and build collagen—this powerful estriol-enriched face cream does it all

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NEWM4 Eye Cream Rx

M4 Eye Cream Rx

Estriol + Peptides

$90.00

90 days of treatment, $30 per month

Target fine lines and boost collagen with a lifting and renewing cream that smooths and firms delicate skin

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$30 OFFDaily Strength Duo Hero

Daily Strength Duo

M4 Face Cream Rx & M4 Eye Cream Rx

$210.00 $240.00

90 days of treatment, $70 per month

This estriol-based set is clinically proven to boost collagen production, deeply hydrate, and increase elasticity

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Oprah's O-wardsM4 Face Serum Rx

M4 Face Serum Rx

Estriol + Peptides + Hyaluronic Acid

$159.00

90 days of treatment, $53 per month

Smooth, firm and repair your skin with this deeply hydrating serum packed with collagen-boosting estriol

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Tretinoin Face Cream Rx

Tretinoin Face Cream Rx

Tretinoin + Niacinamide

$90.00

90 days of treatment, $30 per month

Topical treatment compounded with niacinamide and aloe for acne, fine lines, hyperpigmentation, and discoloration

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NEWRosacea Face Cream Rx

Rosacea Face Cream Rx

Azelaic Acid + Metronidazole + Ivermectin

$99.00

90 days of treatment, $33 per month

Triple-action prescription rosacea cream clinically designed to target redness, inflammation, and sensitivity

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Glow & Go Set Hero
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M4 Eye Cream RxM4 Face Cream RxM4 Face Serum Rx

Glow & Go Set

$299.00

90 days of treatment, $99 per month

$399 ValueSave $100

Aging has never looked this good. Together, our M4 Face Cream Rx, M4 Face Serum Rx, and M4 Eye Cream Rx boost collagen production, restore hydration, improve elasticity, and support hormonal skin repair.

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Free shipping

Includes unlimited messaging with a menopause-trained doctor

SAVE 25% when you subscribe to threee M4 best sellers.

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Estriol Ingredient

ESTRIOL: A TRUE GAME CHANGER

Estriol, a form of estrogen and the powerhouse ingredient in our M4 products, builds collagen, increases elasticity, and restores moisture.

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Precision Skincare at Every Step of Your Routine

Once Daily

Treat the Eye Area

On clean skin, apply 1 pump of M4 Eye Cream Rx to each under eye and lid area

Morning Routine

Two Hydration Options

For lighter hydration, apply 2 pumps of  M4 Face Serum Rx

For deeper hydration, apply 2 pumps of M4 Face Cream Rx

Apply to a clean, dry, face and neck

Evening Routine

Lock In & Protect

Apply 2 pumps of M4 Face Cream Rx

Apply a moisturizer or retinoid—like Alloy's Tretinoin Face Cream Rx—as directed by your provider

Apply to a clean, dry, face and neck

Woman with Skincare

You Deserve Skincare That Actually Works

Prescription-strength care, designed for the skin you have right now.

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The Reviews Are In, And They're Glowing

I have been using Alloy M4 and it’s unbelievable. Literally a miracle for my skin.

- Deborah C.

Obsessed with Alloy's M4 cream. My skin is ✨GLOWING✨

- Harprett T

This has been a game changer for my 52 year old skin. Wow!

- Laura T.

I have been using the M4 for 4 months now. I’m glowing! My face looks smoother and hydrated...So happy I found this magic in a bottle.

- Stacy M.

Frequently Asked Questions

Want Radiant, Glowing Skin Again?

Your skin isn't aging, it's changing. Estriol gives it exactly what it's been missing.

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