Prescription-Strength Skincare
Alloy's M4 skincare is the first estriol-powered formula clinically proven to rebuild collagen, restore elasticity, and visibly reduce wrinkles in just 12 weeks.
Starting at $30 per month.
Featured in Oprah's O-wards
Menopause-Expert Doctors
Simple Intake Form
HSA and FSA Eligible
Transform Your Skin
Target fine lines, wrinkles, and signs of aging with prescription power

M4 Face Cream Rx
Estriol
$150.00

M4 Body Treatment Rx
Estriol + Peptides
$195.00

M4 Eye Cream Rx
Estriol + Peptides
$90.00

M4 Face Serum Rx
Estriol + Peptides + Hyaluronic Acid
$159.00

Tretinoin Face Cream Rx
Tretinoin + Niacinamide
$90.00

Rosacea Face Cream Rx
Azelaic Acid + Metronidazole + Ivermectin
$99.00

Targeted Treatments, Smart Savings
Get radiant, resilient skin with exclusive sets designed for visible results

Head to Toe Set
M4 Face Cream Rx, M4 Eye Cream Rx & M4 Body Treatment Rx
$335.00 $435.00

Glow & Go Set
M4 Face Cream Rx, M4 Face Serum Rx, & M4 Eye Cream Rx
$299.00 $399.00

Daily Strength Duo
M4 Face Cream Rx & M4 Eye Cream Rx
$210.00 $240

Power Pair
M4 Face Cream Rx & Tretinoin Face Cream Rx
$210.00 $240.00
The Reviews Are In, and They're Glowing
I have been using Alloy M4 and it’s unbelievable. Literally a miracle for my skin.
- Deborah C.
Obsessed with Alloy's M4 cream. My skin is ✨GLOWING✨
- Harprett T
This has been a game changer for my 52 year old skin. Wow!
- Laura T.
I have been using the M4 for 4 months now. I’m glowing! My face looks smoother and hydrated...So happy I found this magic in a bottle.
- Stacy M.
Precision Skincare in Every Step
Treat the Eye Area
On clean skin, apply 1 pump of M4 Eye Cream Rx to each under eye and lid area
Select Your M4 Base Treatment
AM routine or lighter hydration: Apply 2 pumps of M4 Face Serum Rx
PM routine or deeper hydration: Apply 2 pumps of M4 Face Cream Rx
Lock in & Protect
AM: Follow with a moisturizer, SPF, and makeup as needed
PM: Apply a moisturizer or retinoid, like Alloy's Tretinoin Face Cream Rx
As directed by your provider
Treat the Body
Apply 1 pump of M4 Body Treatment Rx to hands, arms, chest, legs above the knees, and stomach

Frequently Asked Questions
Disclosures
*2024 Study: Based on a 12-week randomized, double-blind, placebo-controlled clinical study (n=86) using Corneometer®, Cutometer®, and dermaspectrophotometer instrumental measurements, investigator clinical grading, and subject self-asses
2025 Study: Based on a 12-week clinical study (n=34) using Corneometer®, Moisturemeter EpiD, Cutometer®, and Antera 3D® instrumental measurements, expert visual and tactile grading, and self-assessment questionnaire.
2026 Study: Based on a 12-week clinical study (n=38) using Corneometer®, Moisturemeter EpiD, Cutometer®, and Antera 3D® instrumental measurements, expert visual and tactile grading, and self-assessment questionnaire.
























