Your Skin Deserves

Prescription-Strength Skincare

Alloy's M4 skincare is the first estriol-powered formula clinically proven to rebuild collagen, restore elasticity, and visibly reduce wrinkles in just 12 weeks.

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Clinically Proven M4 Skincare

Alloy became the first company to offer skincare with estriol—and independent tests showed significant, measurable results. In just 12 weeks, women using M4 creams saw visibly firmer, smoother, more radiant skin.

23%

Increase in under-eye hydration

UP TO86%

Boost in skin elasticity and bounce

UP TO25%

Reduction in wrinkles around eyes

68%

Improvement in overall skin health

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Featured in Oprah's O-wards

Menopause-Expert Doctors

Simple Intake Form

HSA and FSA Eligible

Transform Your Skin

Target fine lines, wrinkles, and signs of aging with prescription power

BEST SELLER

M4 Face Cream Rx

Estriol

Monthly price $50.00

Each bottle is a 3 month supply. Billed at $150.00

Restore elasticity, hydrate deeply and build collagen—this powerful estriol-enriched face cream does it all

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NEW

M4 Eye Cream Rx

Estriol + Peptides

Monthly price $30.00

Each bottle is a 3 month supply. Billed at $90.00.

Target fine lines and boost collagen with a lifting and renewing cream that smooths and firms delicate skin

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Oprah's O-wards

M4 Face Serum Rx

Estriol + Peptides + Hyaluronic Acid

Monthly price $53.00

Each bottle is a 3 month supply. Billed at $159.00.

Smooth, firm and repair your skin with this deeply hydrating serum packed with collagen-boosting estriol

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Tretinoin Face Cream Rx

Tretinoin + Niacinamide

Monthly price $30.00

Each bottle is a 3 month supply. Billed at $90.00.

Topical treatment compounded with niacinamide and aloe for acne, fine lines, hyperpigmentation, and discoloration

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NEW

Rosacea Face Cream Rx

Azelaic Acid + Metronidazole + Ivermectin

Monthly price $33.00

Each bottle is a 3 month supply. Billed at $99.00.

Triple-action prescription rosacea cream clinically designed to target redness, inflammation, and sensitivity

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$100 OFF

Glow & Go

M4 Face Cream Rx, Face Serum Rx, & Eye Cream Rx

Monthly price $99.66 $133.00

Each bottle is a 3 month supply. Billed at $299.99.

Our next-generation anti-aging treatments improve deep hydration, reduce fine lines, and deliver visibility firmer skin.

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ESTRIOL: A TRUE GAME CHANGER

Estriol, a form of estrogen and the powerhouse ingredient in our M4 products, builds collagen, increases elasticity, and restores moisture.

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Targeted Treatments, Smart Savings

Get radiant, resilient skin with exclusive sets designed for visible results

$30 OFF

Daily Strength Duo

M4 Face Cream Rx & M4 Eye Cream Rx

Monthly price $70.00 $80.00

Each bottle is a 3 month supply. Billed at $210.00.

This estriol-based set is clinically proven to boost collagen production, deeply hydrate, and increase elasticity

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$30 OFF

Power Pair

M4 Face Cream Rx & Tretinoin Face Cream Rx

Monthly price $70.00 $80.00

Each bottle is a 3 month supply. Billed at $210.00.

A powerhouse duo that delivers surface renewal and deep repair for younger-looking, smoother skin

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$30 OFF

Advanced Essentials

M4 Eye Cream Rx & Face Serum Rx

Monthly price $73.00 $83.00

Each bottle is a 3 month supply. Billed at $219.00.

New M4 additions boost collagen production and target fine lines and dullness with estriol, peptides, and hyaluronic acid

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$100 OFF

Glow & Go

M4 Face Cream Rx, Face Serum Rx, & Eye Cream Rx

Monthly price $99.66 $133.00

Each bottle is a 3 month supply. Billed at $299.00.

Our next-generation anti-aging treatments improve deep hydration, reduce fine lines, and deliver visibility firmer skin.

Start Now

The Reviews Are In, and They're Glowing

I have been using Alloy M4 and it’s unbelievable. Literally a miracle for my skin.

- Deborah C.

Obsessed with Alloy's M4 cream. My skin is ✨GLOWING✨

- Harprett T

This has been a game changer for my 52 year old skin. Wow!

- Laura T.

I have been using the M4 for 4 months now. I’m glowing! My face looks smoother and hydrated...So happy I found this magic in a bottle.

- Stacy M.

Precision Skincare in Every Step

Step 1

Treat the Eye Area

On clean skin, apply 1 pump of M4 Eye Cream Rx to each under eye and lid area

Step 2

Select your M4 Base Treatment that suits your morning or evening routine and apply to a clean, dry, face and neck

Best for AM Routine or lighter hydration

Apply 2 pumps of M4 Face Serum Rx

Best for PM Routine or deeper hydration

Apply 2 pumps of M4 Face Cream Rx

Step 3

Finish your routine with the essentials to seal in hydration and protect your skin

AM: Follow with a moisturizer, SPF, and makeup as needed

PM: Apply a moisturizer or retinoid—like Alloy's Tretinoin Face Cream Rx—as directed by your provider

You Deserve Skincare That Actually Works

Prescription-strength care, designed for the skin you have right now.

Find Your Skin Solution

Frequently Asked Questions

What were the results of the clinical studies of M4 products?+

When should I start using the M4 Skincare line?+

What is M4 Estriol Face Cream?+

Why do the M4 skincare products use estriol instead of estradiol?+

Is estriol really as effective as tretinoin?+

Why were the eye cream and the face serum added to the line?+

Can I use M4 with my other favorite products? +

Can I use all three M4 products?+

Who conducted the most recent study?+

Do the M4 products increase estrogen levels?+

Want Radiant Skin Again?

Your skin isn't aging, it's changing. Estriol gives it exactly what it's been missing.

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