Why are compounded GLP-1 medications discouraged?
Compounded GLP-1 medications are discouraged primarily due to safety and quality concerns.
In a recent conversation with Dr. Disha Narang, she explained that:
There is no safety or efficacy data on compounded GLP-1 agents
There have been over a dozen reported deaths associated with compounded versions in recent years
Some compounded products have been found to contain impurities
We do not always know exactly what substances are included in compounded formulations
Now that branded medications are no longer in shortage, there is no clear indication for using compounded alternatives
You can hear this discussion directly here: Navigating Weight Gain in Midlife: Hormones, Health, and Solutions | Liz Plosser & Dr. Disha Narang - Compounded Medications: Risks and Safety
At Alloy, safety is our top priority. Our board-certified physicians follow ACOG and The Menopause Society guidelines and prioritize FDA-approved, well-studied medications whenever possible. When GLP-1 therapy is appropriate, we carefully evaluate each patient to ensure safe, evidence-based care within our clinically supported Weight Care Program. If you would like to explore our medically supervised options, including branded GLP-1s like Wegovy® and Zepbound®, you can learn more here: Weight Care Program Weight Care Program
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