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M4® Head to Toe Set
$335.00 $435.00
3-month supply
EstriolPeptidesPlant BasedBioidentical
Three clinically proven, estriol-based formulas, designed to work together for exceptional results. This head to toe powerhouse team is proven to boost collagen production, hydrate, firm, and restore the skin on your face, eye, and body.
Includes $0 unlimited doctor access
Delivered to your door for free
HSA/FSA Eligible
Confirmed by Experts. Felt by Real Women.
In three independent clinical studies.*
Learn more about M4 Head to Toe Set
What is it: Alloy’s full-body prescription skin protocol, designed for women who want to combat the effects of estrogen loss in menopause and perimenopause. It combines our bestselling M4 eye & face solutions with the first-ever prescription estriol + peptide body treatment.
- M4 Face Cream Rx: Provides deep hydration, rebuilds collagen, and improves elasticity
- M4 Eye Cream Rx: Targets fine lines, thinning skin, and crepiness around the eyes
- M4 Body Treatment Rx: Clinically proven to firm, smooth, hydrate, and restore elasticity on hands, chest, and knees: triple-validated by instruments, experts, and real women.
Who is it for: Women in perimenopause or menopause who notice crepiness, dryness, or loss of firmness on their arms, chest, legs, or knees and want real solutions, not just promises. If you already love M4 Face Cream and want those same clinically proven results on your body, this is the routine you've been waiting for. It's your complete prescription: face and body, done.
What am I getting: 1 bottle M4 Face Cream Rx, 1 bottle M4 Eye Cream Rx, 1 bottle M4 Body Treatment Rx. This is a 3-month supply.
How to get it: Prescription required. A menopause-specialized doctor will review your medical history to determine if this is the right treatment for you.
"I'm 56 and have been using these products for a few months now and am blown away. My skin is soft and hydrated. Big fan. Bravo @myalloy."
- Susie via Instagram
THE M4 DIFFERENCE
The Original Estriol-Based Prescription Skincare Collection
Alloy was the first to harness the power of estriol to combat the effects of hormone loss in your skin.
Created by experts, trusted by doctors, and loved by women everywhere, the M4 collection is designed to work together. Each product is clinically proven to rebuild collagen, restore moisture, increase elasticity, and reduce wrinkles where you need it most.
Active Ingredient: Estriol
Estriol, a form of estrogen and the powerhouse ingredient in our M4 products, builds collagen, increases elasticity, and restores moisture.
Frequently asked questions
The Alloy Promise
At Alloy Health, we believe every woman deserves thoughtful, evidence-based care, and the information she needs to make confident decisions about her health based on facts, not fear.
Our board-certified physicians follow guidelines from leading medical organizations including ACOG and The Menopause Society and recommend treatments tailored to each patient.
Learn more
Disclosures
*2024 Study: Based on a 12-week randomized, double-blind, placebo-controlled clinical study (n=86) using Corneometer®, Cutometer®, and dermaspectrophotometer instrumental measurements, investigator clinical grading, and subject self-asses
2025 Study: Based on a 12-week clinical study (n=34) using Corneometer®, Moisturemeter EpiD, Cutometer®, and Antera 3D® instrumental measurements, expert visual and tactile grading, and self-assessment questionnaire.
2026 Study: Based on a 12-week clinical study (n=38) using Corneometer®, Moisturemeter EpiD, Cutometer®, and Antera 3D® instrumental measurements, expert visual and tactile grading, and self-assessment questionnaire.