EstriolPeptidesPlant Based Bioidentical
M4® Body Treatment Rx
$65.00
Per month
One bottle, billed at a 3-month subscription.
The only prescription estriol + peptide body treatment that delivers results in as little as 8 weeks. Clinically proven to instantly hydrate, visibly smooth, firm, and reduce crepiness where aging shows up most. It’s time to feel confident in your skin again.
Includes $0 unlimited doctor access
Delivered to your door for free
HSA/FSA Eligible
The only Rx body treatment with estriol + peptides.
Real women, real results.
Clinically proven to firm, smooth, and reduce crepiness in a 2026 independent clinical study:*
Learn more about M4 Body Treatment Rx
What is it: A prescription-only, estriol-based anti-aging formula, combining 0.2% estriol in a peptide-rich base, backed by a triple-validated 12-week clinical study. It addresses the impact of hormonal decline on the body. Gentle, fragrance-free, and non-comedogenic.
Who is it for: For any woman experiencing visible skin changes like crepiness, dryness, and loss of firmness, particularly below the neck on the chest, legs, arms, hands or knees, due to estrogen loss in perimenopause or menopause.
What am I getting: 1 bottle (3-month supply) of M4 Body Treatment Rx.
How to get it: Prescription required. A menopause-specialized doctor will review your medical history to determine if this is the right treatment for you.
"I'm 56 and have been using these products for a few months now and am blown away. My skin is soft and hydrated. Big fan. Bravo @myalloy."
- Susie via Instagram
THE M4 DIFFERENCE
The Original Estriol-Based Prescription Skincare Collection
Alloy was the first to harness the power of estriol to combat the effects of hormone loss in your skin.
Created by experts, trusted by doctors, and loved by women everywhere, the M4 collection is designed to work together. Each product is clinically proven to rebuild collagen, restore moisture, increase elasticity, and reduce wrinkles where you need it most.
Active Ingredient: Estriol
Estriol, a form of estrogen and the powerhouse ingredient in our M4 products, builds collagen, increases elasticity, and restores moisture.
Frequently asked questions
The Alloy Promise
At Alloy Health, we believe every woman deserves thoughtful, evidence-based care, and the information she needs to make confident decisions about her health based on facts, not fear.
Our board-certified physicians follow guidelines from leading medical organizations including ACOG and The Menopause Society and recommend treatments tailored to each patient.
Learn more
Disclosure
*Based on a 12-week clinical study (n=38) using Corneometer®, Moisturemeter EpiD, Cutometer®, and Antera 3D® instrumental measurements, expert visual and tactile grading, and self-assessment questionnaire.