M4 Face Cream RxM4 Eye Cream Rx
Daily Strength Duo
$210.00
(90 days of treatment)
$240 Value
This high-performance pair delivers impressive results backed by clinical testing. M4 Face Cream Rx deeply hydrates mature skin, accelerates collagen production, and improves elasticity. M4 Eye Cream Rx combines 1% estriol with wrinkle-fighting peptides to hydrate, firm, and brighten the eye area.
Free shipping
Unlimited messaging with a menopause-trained doctor
SAVE $30 WITH THE DAILY STRENGTH DUO
Pair M4 Face Cream Rx with M4 Eye Cream Rx to target aging from the inside out—smarter skincare, better results, and built-in savings.
The results are in on M4 Eye Cream Rx
In a 2025 independent clinical study, statistically significant improvements* seen in M4 Eye Cream Rx in a 12-week study include:
25%
improvement in wrinkle reduction
33%
improvement in firmness
40%
improvement in more elasticity
40%
improvement in crepiness on eyelids
M4 Eye Cream Rx can be used with or without MHT because it does not impact blood estrogen levels. *Based on expert assessment
Learn more about the Daily Strength Duo
What is it: Our exclusive Daily Strength Duo features two of our most popular prescription-strength skincare products: M4 Face Cream Rx and M4 Eye Cream Rx. Both contain estriol, proven to significantly improve (and even reverse) signs of aging. Our eye cream actually has a full 1% of estriol, boosting its wrinkle-fighting properties.
Who is it for: Women looking to fight signs of aging due to estrogen deficiency.
What am I getting: 1 bottle (45 grams) of M4 Face Cream Rx & 1 bottle (30 grams) of M4 Eye Cream Rx. This set contains a 3-month supply of each.
How to get it: Prescription required. A menopause-trained doctor will review your medical history to determine if this is the right treatment for you.
Estriol Is a Game-changer
Real Customers Love It
Designed for Flexibility
Did you know?
Up to 30% of dermal collagen is lost in the first 5 years of menopause—with another 2.1% lost every year after.
What is Estriol?
Estriol is one of three forms of estrogen our bodies naturally produce, until menopause. Once we hit menopause, we lose up to 30% of our dermal collagen in the first five years alone. And it only goes down from there. The solution to losing estrogen is replenishing it, and that's where estriol comes in.
Research shows that topical estriol can address hormonal aging and helps keep skin resilient, youthful, and balanced. Topical estriol stays on the surface of your skin and doesn’t enter your bloodstream, making it safe for everyday use.
The Alloy Promise
Alloy believes that every woman deserves accurate, up-to-date information and the agency to make her own decisions about her health based on facts, not fear.
All of our board-certified physicians follow ACOG and The Menopause Society guidelines and prescribe only FDA-approved, generic medications for the treatment of menopausal symptoms. The safety of our products is our top priority.
