M4 Face Serum RxM4 Eye Cream Rx
Advanced Essentials Set
$219.00
1 bottle M4 Face Serum Rx & 1 bottle M4 Eye Cream Rx
$249 Value
This powerful duo—M4 Face Serum Rx and M4 Eye Cream Rx—combines prescription-strength estriol, peptides, and hyaluronic acid to hydrate, firm, and visibly rejuvenate skin. Together, they boost collagen and elasticity, smooth fine lines, brighten, and support hormonal skin repair for healthier, more youthful-looking skin.
Free shipping
Unlimited messaging with a menopause-trained doctor
SAVE $30 WITH THE ADVANCED ESSENTIALS SET
Purchase both M4 Face Serum Rx and M4 Eye Cream Rx and save.
The results are in on M4 Eye Cream Rx
In a 2025 independent clinical study, statistically significant improvements* seen in M4 Eye Cream Rx in a 12-week study include:
25%
improvement in wrinkle reduction
33%
improvement in firmness
40%
improvement in more elasticity
40%
improvement in crepiness on eyelids
M4 Eye Cream Rx can be used with or without MHT because it does not impact blood estrogen levels. *Based on expert assessment
Learn more about the Advanced Essentials Set
What is it: The Advanced Essentials Set includes M4 Face Serum Rx and M4 Eye Cream Rx, our new powerful estrogen-based innovations. You’ll save $30 when you buy them together.
Who is it for: Women looking to fight signs of aging due to estrogen deficiency
What am I getting: 1 bottle (45 grams) M4 Face Serum Rx and 1 bottle (15 grams) M4 Eye Cream Rx. This set contains a 3-month supply of each.
How to get it: Prescription required. A menopause-trained doctor will review your medical history to determine if this is the right treatment for you.
Estriol Is a Game-changer
Real Women Love It
Designed for Flexibility
Did you know?
Up to 30% of dermal collagen is lost in the first 5 years of menopause—with another 2.1% lost every year after.
What is Estriol?
Estriol is one of three forms of estrogen our bodies naturally produce, until menopause. Once we hit menopause, we lose up to 30% of our dermal collagen in the first five years alone. And it only goes down from there. The solution to losing estrogen is replenishing it, and that's where estriol comes in.
Research shows that topical estriol can address hormonal aging and helps keep skin resilient, youthful, and balanced. Topical estriol stays on the surface of your skin and doesn’t enter your bloodstream, making it safe for everyday use.
The Alloy Promise
Alloy believes that every woman deserves accurate, up-to-date information and the agency to make her own decisions about her health based on facts, not fear.
All of our board-certified physicians follow ACOG and The Menopause Society guidelines and prescribe only FDA-approved, generic medications for the treatment of menopausal symptoms. The safety of our products is our top priority.
