Hormone decline causes a drop in collagen, leaving skin dry, thin, and crepey. Alloy’s high-performance skincare was developed by menopause-specialized physicians specifically for women in midlife to restore the collagen, moisture, and elasticity they’ve lost.
Build the routine you need, with savings built in.
BEST SELLER
M4 Face Cream Rx
Estriol
$150.00
NEW
M4 Body Treatment Rx
Estriol + Peptides
$195.00
M4 Eye Cream Rx
Estriol + Peptides
$90.00
Oprah's O-wards
M4 Face Serum Rx
Estriol + Peptides + Hyaluronic Acid
$159.00
Tretinoin Face Cream Rx
Tretinoin + Niacinamide
$90.00
Rosacea Face Cream Rx
Azelaic Acid + Metronidazole + Ivermectin
$99.00
Complete Solution Sets, Save $100
$100 OFF
Head to Toe Set
M4 Face Cream Rx, M4 Eye Cream Rx & M4 Body Treatment Rx
$335.00$435.00
$100 OFF
Glow & Go Set
M4 Face Cream Rx, M4 Face Serum Rx, & M4 Eye Cream Rx
$299.00$399.00
KEY M4 SKINCARE INGREDIENT: ESTRIOL
What is Estriol?
Estriol is one of three forms of estrogen our bodies naturally produce, until menopause. Once we hit menopause, we lose up to 30% of our dermal collagen in the first five years alone. And it only goes down from there. The solution to losing estrogen is replenishing it, and that's where estriol comes in.
Research shows that topical estriol can address hormonal aging and helps keep skin resilient, youthful, and balanced. Topical estriol stays on the surface of your skin and doesn’t enter your bloodstream, making it safe for everyday use.
Are the M4 products right for me?+Can I use this with hormone therapy?+What were the results of the clinical studies of M4 products?+When should I start using the M4 Skincare line?+Do I need progesterone?+Is M4 Rx eligible for HSA or FSA reimbursement?+Where is Alloy available?+
Disclosures
*2024 Study: Based on a 12-week randomized, double-blind, placebo-controlled clinical study (n=86) using Corneometer®, Cutometer®, and dermaspectrophotometer instrumental measurements, investigator clinical grading, and subject self-asses
2025 Study: Based on a 12-week clinical study (n=34) using Corneometer®, Moisturemeter EpiD, Cutometer®, and Antera 3D® instrumental measurements, expert visual and tactile grading, and self-assessment questionnaire.
2026 Study: Based on a 12-week clinical study (n=38) using Corneometer®, Moisturemeter EpiD, Cutometer®, and Antera 3D® instrumental measurements, expert visual and tactile grading, and self-assessment questionnaire.
