Ready to get
- Complete Alloy's online assessment in 1 minute.
- A menopause-trained doctor reviews your information and writes your prescription.
- Your prescription is shipped right to your door.
- Free and unlimited follow-up with your doctor.
Topical estriol can help maintain skin health by increasing collagen production, retaining and restoring skin moisture, increasing skin firmness, decreasing pore size, decreasing wrinkle depth, and increasing skin elasticity.
Up to 30%
of dermal collagen is lost during the
first 5 years of menopause
and decreases by an additional 2.1% every year after
For any woman—really, any woman—looking to reverse the effects of estrogen-deficiency in the skin due to menopause, perimenopause, or just aging (loss of collagen, decreased elasticity and moisture, and appearance of wrinkles). M4 works alone or alongside your current menopause treatment plan.Try it now
Adding M4 once, either to your morning or nighttime skincare routine is easy. You can replace your current moisturizer and firming creams with M4 or add it to your regime. It’s safe to use with your other skincare solutions.
During your normal morning skincare routine, apply a pump of M4 to the face and neck when you would normally apply moisturizer (after serums, if you use them). Remember to always complete your morning routine with an SPF.
If you’re using M4 as part of your nighttime routine, apply a pump of M4 when you would normally apply moisturizer (after serums, if you use them) and then follow up with any retinol and/or nighttime moisturizers.Try it now
Lephart ED, Naftolin F. Menopause and the Skin: Old Favorites and New Innovations in Cosmeceuticals for Estrogen-Deficient Skin. Dermatol Ther (Heidelb). 2021 Feb;11(1):53-69. doi: 10.1007/s13555-020-00468-7. Epub 2020 Nov 26. PMID: 33242128; PMCID: PMC7859014.
Rzepecki AK, Murase JE, Juran R, Fabi SG, McLellan BN. Estrogen-deficient skin: The role of topical therapy. Int J Womens Dermatol. 2019 Mar 15;5(2):85-90. doi: 10.1016/j.ijwd.2019.01.001. PMID: 30997378; PMCID: PMC6451761.