What is paroxetine used for menopause hot flashes?

Paroxetine is used as a non-hormonal treatment for menopause hot flashes and night sweats. Here at Alloy, we use it at a much lower dose for hot flashes than the doses typically used for depression, usually 10 mg daily.

It’s an FDA-approved option for vasomotor symptoms, which is the medical term for hot flashes, hot flushes, and night sweats. It’s often considered when estrogen isn’t a good fit because of medical history, or when someone prefers not to use hormone therapy. It’s not usually as effective as hormone therapy, but it does help about 50% of women reduce hot flashes and night sweats, and some people notice improvement within 2 to 4 weeks.

One important caution, paroxetine shouldn’t be taken with tamoxifen because it can interfere with how tamoxifen is processed. And if you’re already taking another SSRI, that needs to be reviewed with a clinician.

For more detail, you can read our paroxetine treatment page and our article on paroxetine for hot flashes vs. depression.

Non-hormonalParoxetine

Paroxetine

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