--- title: "Hyperpigmentation Treatment Cream | Skincare - PIH & Melasma" description: "Get a prescription multi-action treatment for midlife hyperpigmentation—formulated with 0.018% tretinoin, 20% azelaic acid, and 4% niacinamide to help fade the look of dark spots, sun spots, melasma, and post-acne marks" url: "https://www.myalloy.com/solutions/hyperpigmentation-treatment-rx" --- # Hyperpigmentation Treatment Cream | Skincare - PIH & Melasma > Get a prescription multi-action treatment for midlife hyperpigmentation—formulated with 0.018% tretinoin, 20% azelaic acid, and 4% niacinamide to help fade the look of dark spots, sun spots, melasma, and post-acne marks ## Hyperpigmentation Treatment Rx *3-month supply* Type: Prescription (Rx) Tags: 20% Azelaic Acid, 4% Niacinamide, Low-dose Tretinoin Price: $119.00 A triple-action, dermatologist-backed formula developed to target hyperpigmentation at the source. Cumulative sun damage combined with fluctuating estrogen can cause dark spots and melasma to appear all at once. Address hyperpigmentation across your face and chest with one long-lasting treatment. - Includes $0 unlimited doctor access - Delivered to your door for free - HSA/FSA Eligible [Start Now](https://secure.myalloy.com/experience?categories%5B%5D=skin-health&sku-ids%5B%5D=232808f5-efdc-4906-b434-1d93850d2df7&skip-category-select=true&type=intake) ## The highest prescription strength available Powered by 20% azelaic acid to fade stubborn spots and keep them from coming back *Results may vary. Baliña et al. (1991), Int J Dermatol, 30(12):893-5. ## 65% of women rated melasma fading as good or excellent* ## 8 weeks Dark patches may begin to lighten in weeks, with stronger results over 6 months* ## All skin tones Formulated with ingredients that won’t bleach your skin ## Face + chest Developed to reduce hyperpigmentation where it shows up most ## Learn more about Hyperpigmentation Treatment Rx ### Details __What is it:__ A prescription multi-action treatment for midlife hyperpigmentation—formulated with 0.018% tretinoin, 20% azelaic acid, and 4% niacinamide to help fade the look of dark spots, sun spots, melasma, and post-acne marks. __Who is it for:__ For women of all skin tones experiencing visible hyperpigmentation, like sun damage, dark spots, melasma, and overall uneven tone and texture on their face and chest. __What am I getting:__ 1 bottle containing (3-month supply) of Hyperpigmentation Treatment Rx __How to get it:__ Prescription required. A board-certified doctor will review your medical history to determine if this is the right treatment for you. ### Suggested Use - Always follow instructions from your doctor. - Dispense a pea-sized amount onto fingertips. Apply at night to clean, dry skin using your fingers, to forehead, cheeks, and chin - and chest if desired. Avoid eyelids and corners around the mouth and nose. If you have sensitive skin, apply a thin layer of moisturizer or M4 Face Cream or Serum first. - Start with 2–3 nights per week; increase as tolerated - Avoid mixing with other exfoliating actives (e.g., AHAs, BHAs) initially ### Safety Information - Mild tingling or redness may occur during initial use. - Discontinue use if irritation persists. - Patch test before first use. ## A powerful, multi-action formulation Alloy’s Hyperpigmentation Treatment is a triple-active approach designed to address visible discoloration at its source. ### Sun damage Speeds up skin cell turnover to fade the look of sun spots and uneven patches. ### Uneven tone Soothes skin reactivity and calms visible redness while clearing uneven discoloration. ### Dark spots Targets the overactive pigment cells behind dark spots, while leaving your normal skin tone alone. ### Melasma Helps fade melasma without the bleaching risk of hydroquinone. ![Hyperpigmentation Ingredients](https://images.ctfassets.net/md0kv0ejg0xf/4wG0Y0Si3ZYjx70O5DjdhP/0005bca3f41c7f8cfccfd9145746ca84/Ingredients-Module_750x750_Hyperpigmentation-Treatment_Mobile.png) *THE FORMULA* ### The prescription power trio 20% azelaic acid fades hyperpigmentation at its source while 4% niacinamide restores your skin barrier, and a low-dose of tretinoin accelerates cellular turnover. ### “Decades of sun damage and shifting hormones are common causes of hyperpigmentation. Azelaic acid, tretinoin, and niacinamide are the actives I trust to reduce it in months. Dr. Corinne Erickson Board-certified dermatologist (FAAD), Menopause Society Certified Practitioner (MSCP) and Alloy Health Medical Advisor, Dermatology ![Hyperpigmentation Quote](https://images.ctfassets.net/md0kv0ejg0xf/22I6ctustpWovqmwYMWYI8/197723131ec5a42d4db6a0afea3cf624/Social-Proof-Module_768x500_Hyperpigmentation-Treatment_2x.png) ## Real Alloy Customers. Real Results. ## Spotless skin after 30 is simpler than you think Answer a few questions to connect with a board-certified doctor who'll oversee your prescription. Message them anytime, before or after you start. [Start Now](https://secure.myalloy.com/experience?categories%5B%5D=skin-health&sku-ids%5B%5D=232808f5-efdc-4906-b434-1d93850d2df7&skip-category-select=true&type=intake) ## Frequently asked questions ### How do I know if Hyperpigmentation Treatment Rx is right for me? Those with dark spots, sun spots, melasma, post-acne marks, or uneven tone on the face or chest are good candidates. As with any prescription product, a skin assessment is required first. A menopause-specialized doctor reviews the assessment and confirms medical eligibility for the Rx formula before anything ships. ### Why no hydroquinone? Is this as effective? Hydroquinone works, but it comes with bleaching risk, mandatory breaks, and rebound pigmentation when stopped. We built ours around 20% azelaic acid, the highest prescription strength, which went head-to-head with 4% hydroquinone in a clinical study and held its own, with 65% of women rating their melasma fading as good or excellent. No bleaching, no cycling off.* ### How is this different from Tretinoin Face Cream Rx? Do I need both? They do different jobs. Tretinoin Face Cream Rx is a retinoid for overall renewal: fine lines, texture, acne. Hyperpigmentation Treatment Rx is built for pigment: 20% azelaic acid targets overactive pigment cells, a low dose of tretinoin keeps turnover moving, and niacinamide keeps skin calm. These aren't applied to the same area at the same time; a doctor will advise whether to switch between them, or use tretinoin on the face and this one on the chest. ### How long until I see a difference? Dark patches can begin to lighten in as little as 8 weeks, and the best results continue through 6 months of consistent use. Individual results may vary. ### Can I use it on my chest? Yes. It’s one cream for face and chest, which is where midlife sun damage and dark spots tend to show up most. Apply at night to clean, dry skin. ### Can I use this with hormone therapy? Yes. Hyperpigmentation Treatment Rx works in the skin, not the bloodstream, so it’s safe alongside hormone replacement therapy (HRT) and vaginal estrogen. ### Will I be charged before I'm approved? No. There's no charge until a doctor confirms eligibility to receive the product. The review is included in the visit, not billed separately. ### Where is Alloy available? All 50 U.S. states and D.C. (Global users can still access our content & resources.) --- *This is a markdown version of [https://www.myalloy.com/solutions/hyperpigmentation-treatment-rx](https://www.myalloy.com/solutions/hyperpigmentation-treatment-rx) for AI/LLM consumption.*