--- title: "Estradiol Vaginal Cream: Prescription Estrogen Cream | Alloy" description: "Relieve vaginal dryness, discomfort, and GSM with prescription-strength estradiol vaginal cream. The gold standard estrogen cream for menopause relief. Low-dose and effective" url: "https://www.myalloy.com/solutions/estradiol-vaginal-cream" --- # Estradiol Vaginal Cream: Prescription Estrogen Cream | Alloy > Relieve vaginal dryness, discomfort, and GSM with prescription-strength estradiol vaginal cream. The gold standard estrogen cream for menopause relief. Low-dose and effective ## Estradiol Vaginal Cream Type: Prescription (Rx) Tags: Plant Based, Bioidentical , FDA-Approved Price: $39.99 __Per month__ Each tube is a 3 month supply, billed at $119.97. Up to 84% of women experience genitourinary symptoms of menopause — vaginal dryness, itching, burning, painful sex, frequent UTIs, yet most go untreated. This localized estradiol cream delivers fast, effective relief. *Note: Pharmaceutical tubes are sealed at the crimp during manufacturing and tube will not have a metal seal.* - Includes $0 unlimited doctor access - Delivered to your door for free - HSA/FSA Eligible Medically reviewed by: [Dr. Michelle Montville](https://www.myalloy.com/expert/michelle-montville), Prescribing Physician [Start Now](https://secure.myalloy.com/experience?categories%5B%5D=vaginal-health%2Csexual-health&sku-ids%5B%5D=b05fc1ea-c11f-4fa7-bb93-0f0494a62cff%2C011efcaf-50e3-4f76-bb57-c8af33141f41&skip-category-select=true&type=intake) ## Best for - Vaginal Issues - Painful Sex - Bladder Issues ## Learn more about the Estradiol Vaginal Cream ### Details __What is it:__ Estradiol cream is an FDA-approved, plant-based, bio-identical, local hormone treatment for the alleviation of genitourinary symptoms (vaginal dryness, itching, burning, painful sex, frequent UTIs) due to menopause. __Who is it for:__ Vaginal estradiol cream is recommended for any woman experiencing vaginal symptoms like dryness, burning, itching, frequent UTIs and painful sex. __What am I getting:__ 1 tube containing 42.5 grams (45 uses) of estradiol cream (0.01%) designed to last three months of use. __How to get it:__ Prescription required. A menopause-trained doctor will review your medical history to determine if this is the right treatment for you. ### Suggested Use Use applicator to insert vaginal cream inside the vagina. You can also apply anywhere you are feeling discomfort, including the outside or inner vulva, as directed by your doctor. The suggested use is every other day, but it can be used as needed. ### Safety Information Your menopause-trained doctor will determine the best treatment plan for you. Vaginal estradiol cream is a very low-dose topical estradiol cream that is considered by the Menopause Society to be safe for almost all women. The small amount of estrogen in the vaginal cream is absorbed locally rather than systemically. ### A simple, low-dose cream The small amount of estrogen in Estradiol Vaginal Cream is absorbed locally, and effectively treats the symptoms of the Genitourinary Syndrome of Menopause (vaginal dryness, itching, painful sex, frequent UTIs). ### Multi-symptom relief Vaginal estradiol is FDA-approved to treat vaginal dryness, pain, painful sex, itching and frequent UTIs by rejuvenating the tissue in and around the vagina, increasing moisture and improving elasticity. It also restores the vaginal pH to an optimal level. ### See Results in as Little as 12 Weeks! While results timelines vary, most people see significant improvements in their vaginal health within three months. ### Safe to use with HRT Estrogen in the cream is non-systemic, meaning you can safely use it with Hormone Replacement Therapy. ### O-mazing + Estradiol Vaginal Cream = the perfect combo for improved sexual health Perimenopause, menopause, and aging mean the possibility of issues like decreased desire, painful sex, dryness, and bladder issues. Our sexual and vaginal health treatments are specially formulated to: - Relieve dryness, itching, and burning - Alleviate painful sex - Decrease frequent UTIs - Treat bladder issues - Stimulate natural lubrication - Enhance arousal and satisfaction We love 'em on their own, but they're better together. Get $40 off when you buy O-mazing and Estradiol Vaginal Cream together. [Get the Sexual Health Bundle](https://secure.myalloy.com/experience?categories%5B%5D=vaginal-health%2Csexual-health&sku-ids%5B%5D=b05fc1ea-c11f-4fa7-bb93-0f0494a62cff%2C011efcaf-50e3-4f76-bb57-c8af33141f41&skip-category-select=true&type=intake) ![Sexual Health Set Bundle No Background](https://images.ctfassets.net/md0kv0ejg0xf/6kHDHiGSJMz1pqVFOnNgPG/ce860993f2fba30be4dfaf6a6377a988/sexual_health_bundle_Compressed-min.png) ![Just feet](https://images.ctfassets.net/md0kv0ejg0xf/2gWU3f2rG549ZqsHJv8leJ/cd4e94eace170ca0d9b9c5da7d39e30c/desktop_stat_img-feet.jpg) *Did you know?* ### 80% of women will see improvement in vaginal symptoms within 4-12 weeks of starting treatment ![Estradiol Molecule](https://images.ctfassets.net/md0kv0ejg0xf/3lJs6jy0PqQHtyAE7nsVKC/9881042f0261a3760a85dfffc73556b3/Estradiol_molecule.svg) ### What is Estradiol? Estradiol is the primary estrogen produced by the body and is considered to be the most powerful. The estradiol in Alloy-prescribed products is molecularly identical to the estradiol your body produces naturally.

Our bodies need estrogen for the normal function of multiple organ systems, including our brains, bones, and hearts. As we go through menopause, our estrogen levels dramatically decrease, and this is what causes symptoms. Replenishing your body's natural estrogen in small doses can help you feel your best and stay healthy for longer. ## More on Estradiol Vaginal Cream ### [Do I need Estradiol Vaginal Cream?](https://www.myalloy.com/blog/menopause-treatment-vaginal-estrogen-cream) ### [Vaginal Itching and Menopause: Causes and Relief](https://www.myalloy.com/blog/vaginal-itching-and-menopause) ### [How To Prevent Vaginal Dryness](https://www.myalloy.com/blog/how-to-prevent-vaginal-dryness-during-menopause) ### [Understanding Your Libido and How To Improve It](https://www.myalloy.com/blog/why-is-my-libido-low-understanding-sexual-desire-and-the-connections-to) ### How Alloy Works We make it easy to connect directly with a menopause-specialized physician. [Find Your Plan](https://secure.myalloy.com/experience) **Tell Us About Yourself (5-10 minutes)** Fill out an intake form to share your symptoms, health history, and goals **Get a Treatment Plan (less than 12 hours)** Your expert doctor will create a personalized plan based on your needs. **Free Delivery to Your Door** Get your prescriptions sent right to your home with free shipping **24/7 Care + Ongoing Support** Get unlimited access to your doctor, support groups, and more ## Frequently asked questions ### How do I know if Estradiol Vaginal Cream is right for me? Your menopause-trained doctor will review your symptoms and medical history and help determine the best treatment plan for you. If you are experiencing vaginal symptoms of menopause, including itching, burning, dryness, painful sex, and/or frequent UTIs, you are a candidate for topical vaginal estradiol. It is safe for everyone to use and is very effective. ### Can I use Estradiol vaginal cream with other forms of hormone treatment? Estradiol vaginal cream can be used alongside any other treatments prescribed by Alloy, including Menopausal Hormone Therapy and M4. ### What is Estradiol vaginal cream and why is it prescribed? Estradiol vaginal cream is localized (non-systemic), topical estradiol cream. It is prescribed to provide effective relief from genitourinary syndrome of menopause, including symptoms like vaginal dryness, itching, burning, and for the prevention of frequent UTIs. It is very effective and safe to use. ### Do I need progesterone? If you are using Estradiol vaginal cream and are not taking systemic MHT, you do not need progesterone. But, if you’re already taking it, it is totally fine to use them together! ### Is estradiol vaginal cream eligible for HSA or FSA reimbursement? Yes! Medications prescribed by a licensed provider are eligible to be paid for or reimbursed by your HSA or FSA. Your invoice is available to download and include when you submit to your plan for reimbursement. If you require more information, please contact us at support@myalloy.com and we will assist you. Note: The IRS defines which medical expenses are eligible under an HSA or FSA and the products carried on Alloy are in compliance with these requirements. However, these plans can vary and some may not allow all eligible HSA or FSA expenses. It's important to always check with your benefits administrator to determine which expenses are eligible before you shop. ### Where is Alloy available? All 50 U.S. states and D.C. (Global users can still access our content & resources.) [Learn More](https://myalloy.zendesk.com/hc/en-us) ## What our customers are saying: ### The Alloy Promise At Alloy Health, we believe every woman deserves thoughtful, evidence-based care, and the information she needs to make confident decisions about her health based on facts, not fear. Our board-certified physicians follow guidelines from leading medical organizations including ACOG and The Menopause Society and recommend treatments tailored to each patient. [Learn more](https://www.myalloy.com/compounded-products) ![The Alloy Promise](https://images.ctfassets.net/md0kv0ejg0xf/5S3J54W7j0MPpyLNbGg2WF/96e117713fd5bd6ddfc07bb92e5b73e6/Group_80197.png) --- *This is a markdown version of [https://www.myalloy.com/solutions/estradiol-vaginal-cream](https://www.myalloy.com/solutions/estradiol-vaginal-cream) for AI/LLM consumption.*