---
title: "Non-GLP-1 Oral Weight Loss Medication Side Effects"
description: "Learn about common side effects of non-GLP-1 oral weight loss medications like phentermine topiramate and bupropion naltrexone, and how to manage them."
url: "https://www.myalloy.com/knowledge-base/what-side-effects-can-occur-with-non-glp-1-oral-weight-loss-medications"
---

# Non-GLP-1 Oral Weight Loss Medication Side Effects

> Learn about common side effects of non-GLP-1 oral weight loss medications like phentermine topiramate and bupropion naltrexone, and how to manage them.

## What side effects can occur with non-GLP-1 oral weight loss medications?

Non GLP 1 oral weight loss medications, such as **phentermine topiramate** or **bupropion naltrexone**, can have a different side effect profile compared to injectable GLP 1s.

Some possible side effects include:

- **Palpitations**
- **Tremors**
- **Difficulty sleeping**
- **Dry mouth**

As discussed in this helpful video chapter on managing oral medication side effects, dosing is key. These medications are typically started at a very low dose and increased slowly based on how you are feeling. There is no rush to reach the highest dose, and if you do not feel well, your doctor may adjust or stop the medication.

You can watch the full explanation here: [Navigating Weight Gain in Midlife: Hormones, Health, and Solutions | Liz Plosser & Dr. Disha Narang - Common Side Effects of Weight Loss Medications](https://www.youtube.com/watch?v=kBRBZbcbHH8&t=2038s)


[Watch video](https://www.youtube.com/watch?v=kBRBZbcbHH8&t=2038s)

Here at Alloy, our Weight Care program is designed to provide close medical supervision, personalized dosing, and ongoing support to help minimize side effects and make sure your treatment feels manageable and safe. You can learn more about our comprehensive approach here: [Alloy Weight Care Program](https://www.myalloy.com/weight)

[Find Your Plan](https://secure.myalloy.com/experience)

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This answer was created using the following resources:

- [What’s Really Behind Menopausal Weight Gain—and How to Treat It | Dr. Alexandra Sowa - Managing Side Effects and Medication Dosing](https://www.youtube.com/watch?v=PQ60VjfnliA)
- [Navigating Weight Gain in Midlife: Hormones, Health, and Solutions | Liz Plosser & Dr. Disha Narang - Common Side Effects of Weight Loss Medications](https://www.youtube.com/watch?v=kBRBZbcbHH8)
- [Are GLP-1 Weight Loss Medications Safe? | GLP-1 Side Effects](https://www.myalloy.com/blog/are-glp-1-medications-safe-and-what-about-side-effects)
- [How GLP-1s Support Weight Loss & Metabolic Health](https://www.myalloy.com/blog/how-do-glp-1s-work)

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