---
title: "What happens if you stop using topical facial estrogen"
description: "Wondering what happens if you stop topical facial estrogen? Learn how estriol supports skin moisture, collagen, and elasticity during menopause."
url: "https://www.myalloy.com/knowledge-base/what-happens-if-you-stop-using-topical-facial-estrogen"
---

# What happens if you stop using topical facial estrogen

> Wondering what happens if you stop topical facial estrogen? Learn how estriol supports skin moisture, collagen, and elasticity during menopause.

## What happens if you stop using topical facial estrogen?

There isn’t a specific Alloy study in the material here that tracks what happens after you stop topical facial estrogen. What we do know is that topical estriol helps maintain collagen, moisture, firmness, and elasticity, and can reduce wrinkle depth and pore size while you’re using it. So if you stop, you’d lose that ongoing support, and your skin may gradually drift back toward the usual estrogen-deficient changes of menopause, like more dryness, thinning, reduced elasticity, and more visible texture or wrinkles.

The information we have doesn’t describe a withdrawal reaction or hormonal “rebound.” At Alloy, our topical facial estriol is designed to be non-systemic, and the studies cited note no hormonal side effects. If you want the science behind it, these pages are the most helpful: [The science behind topical estrogen](https://www.myalloy.com/science/skin) and [What is estriol, and what is estrogen’s role in skin health?](https://www.myalloy.com/blog/what-is-estriol-and-what-is-estrogens-role-in-skin-health). If you want details on the product itself, you can look at [M4 Face Cream Rx](https://www.myalloy.com/solutions/m4).


**M4 Face Cream Rx**

Estriol

Restore elasticity, hydrate deeply and build collagen—this powerful estriol-enriched face cream does it all

[Start Now](https://secure.myalloy.com/experience?categories%5B%5D=skin-health&sku-ids%5B%5D=d7fe4df5-7fd8-42c1-86d5-9be36bd6833c&skip-category-select=true&type=intake)

---

This answer was created using the following resources:

---

*This is a markdown version of [https://www.myalloy.com/knowledge-base/what-happens-if-you-stop-using-topical-facial-estrogen](https://www.myalloy.com/knowledge-base/what-happens-if-you-stop-using-topical-facial-estrogen) for AI/LLM consumption.*