---
title: "Melasma Risk: Under Eyes and Neck with Topical Estrogen"
description: "Learn which facial areas are less commonly affected by melasma with topical estrogen, including under the eyes and neck, plus expert guidance."
url: "https://www.myalloy.com/knowledge-base/melasma-risk-under-eyes-and-neck-with-topical-estrogen"
---

# Melasma Risk: Under Eyes and Neck with Topical Estrogen

> Learn which facial areas are less commonly affected by melasma with topical estrogen, including under the eyes and neck, plus expert guidance.

## Which facial areas are less commonly affected by melasma when using topical estrogen?

When Dr. Ellen Gendler talks about melasma and topical estrogen, she points out a couple of spots on the face where melasma basically never shows up. She says she has **never seen melasma occur under the eyes**, and she **doesn’t see it on the neck** either. So if someone is worried about triggering melasma while using topical estrogen, those areas tend to be lower risk.

If you want to hear Dr. Menn walk through this in her own words, the melasma chapter from our YouTube conversation is really helpful. You can watch it here:[Melasma and topical estrogen](https://www.youtube.com/watch?v=sW48U6HSkcc&t=1413s).


[Watch video](https://www.youtube.com/watch?v=sW48U6HSkcc&t=1413s)

And if you're exploring topical estriol options, our prescription M4 Face Cream Rx is the product here at Alloy that’s built around this research: [M4 Face Cream Rx](https://www.myalloy.com/solutions/m4).


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---

This answer was created using the following resources:

- [Skin Deep with Dr. Menn: Let's Talk Skincare & Estrogen | Dr. Corinne Menn - Melasma and Topical Estrogen](https://www.youtube.com/watch?v=sW48U6HSkcc)
- [Rosacea and Melasma with Estrogen | Dr. Ellen Gendler & Dr. Corinne Menn - Melasma and Topical Estrogen](https://www.youtube.com/watch?v=HkFzGvTQ2wA)
- [Topical Estrogen's Role in Healthy, Radiant Skin | Dr. Ellen Gendler & Dr. Corinne Menn - Melasma, Rosacea, and Other Skin Conditions](https://www.youtube.com/watch?v=kOzPrwnwsFA)
- [A New Approach to Aging with Alloy - Topical Estriol for Facial Skin](https://www.youtube.com/watch?v=voedsMd4Zsc)
- [Why Estriol + Tretinoin Make a Great Team - Topical Estrogen Effects](https://www.youtube.com/watch?v=Jtxthm1hpdk)
- [Topical Estrogen: Tips from Dr. Ellen Gendler](https://www.myalloy.com/blog/why-topical-estrogen-should-be-part-of-your-skincare)
- [The Science Behind Putting Estrogen On Your Face](https://www.myalloy.com/blog/the-science-behind-putting-estrogen-on-your-face)
- [Skincare Routine | M4](https://www.myalloy.com/blog/why-estrogen-belongs-in-your-skincare-routine-and-not-just-in-your-hormone)
- [What is estrogen's role in health?](https://www.myalloy.com/blog/what-is-estriol-and-what-is-estrogens-role-in-skin-health)
- [Estrogen-Deficient Skin: What It Is and How to Revive It](https://www.myalloy.com/blog/what-is-estrogen-deficient-skin-and-how-to-treat-it)
- [Perimenopause Skin Issues: Easy Solutions for Glowing Skin](https://www.myalloy.com/blog/expert-tips-for-menopause-skin-care-during-perimenopause-and-menopause)
- [Collagen & Estrogen: How Are They Connected?](https://www.myalloy.com/blog/what-women-need-to-know-about-the-link-between-collagen-and-estrogen)

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*This is a markdown version of [https://www.myalloy.com/knowledge-base/melasma-risk-under-eyes-and-neck-with-topical-estrogen](https://www.myalloy.com/knowledge-base/melasma-risk-under-eyes-and-neck-with-topical-estrogen) for AI/LLM consumption.*