---
title: "Long-term topical estriol and apparent age"
description: "Explore how long-term topical estriol may improve skin texture, elasticity, and wrinkles, helping skin look younger with topical estrogen use."
url: "https://www.myalloy.com/knowledge-base/long-term-topical-estriol-and-apparent-age"
---

# Long-term topical estriol and apparent age

> Explore how long-term topical estriol may improve skin texture, elasticity, and wrinkles, helping skin look younger with topical estrogen use.

## How did observers perceive the impact of long-term topical estriol use on apparent age?

I don't have a specific observer-rating result about "apparent age" in the material here.

What I can say is that the long-term topical estriol results in our content were described as making skin look younger overall. In the video summary about 2.5 years of use, consistent estriol use was linked to better texture, elasticity, brightness, and overall appearance, with the user saying it made her look and feel younger. Our science page also notes that after 6 months of topical estrogen use, wrinkle depth and pore size decreased by 61 to 100%, along with improved firmness and elasticity.

If you want the broader background, these are the most relevant pages:
[The science behind putting estrogen on your face](https://www.myalloy.com/blog/the-science-behind-putting-estrogen-on-your-face)
[The science behind topical estrogen](https://www.myalloy.com/science/skin)
[M4 Estriol Face Cream](https://www.myalloy.com/solutions/m4)


**M4 Face Cream Rx**

Estriol

Restore elasticity, hydrate deeply and build collagen—this powerful estriol-enriched face cream does it all

[Start Now](https://secure.myalloy.com/experience?categories%5B%5D=skin-health&sku-ids%5B%5D=d7fe4df5-7fd8-42c1-86d5-9be36bd6833c&skip-category-select=true&type=intake)

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This answer was created using the following resources:

- [How Our Co-Founder Discovered the Original Estriol Face Cream](https://www.youtube.com/watch?v=97Ow0AE2Yhk)
- [My 2.5 Year Results From Using M4 Estriol Face Cream](https://www.youtube.com/watch?v=VpU_XE0PyPk)
- [Topical Estrogen: Tips from Dr. Ellen Gendler](https://www.myalloy.com/blog/why-topical-estrogen-should-be-part-of-your-skincare)
- [The Science Behind Putting Estrogen On Your Face](https://www.myalloy.com/blog/the-science-behind-putting-estrogen-on-your-face)

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*This is a markdown version of [https://www.myalloy.com/knowledge-base/long-term-topical-estriol-and-apparent-age](https://www.myalloy.com/knowledge-base/long-term-topical-estriol-and-apparent-age) for AI/LLM consumption.*