---
title: "Alloy M4 Cream: Active Ingredient and Concentration"
description: "Learn the active ingredient in Alloy M4 Face Cream Rx: 0.3% estriol. See what it is, how it’s used, and where to find full product details."
url: "https://www.myalloy.com/knowledge-base/alloy-m4-cream-active-ingredient-and-concentration"
---

# Alloy M4 Cream: Active Ingredient and Concentration

> Learn the active ingredient in Alloy M4 Face Cream Rx: 0.3% estriol. See what it is, how it’s used, and where to find full product details.

## What is the active ingredient and concentration in Alloy’s prescription M4 cream?

Here at Alloy, our prescription M4 Face Cream Rx uses **estriol as the active ingredient**, and the concentration is **0.3 percent estriol**.

That exact percentage is mentioned in our video content, and if you want to hear it directly, you can watch this chapter about the cream here: [About Alloy M4 Cream](https://www.youtube.com/watch?v=ZM5sP8eCJEE&t=8s).


[Watch video](https://www.youtube.com/watch?v=ZM5sP8eCJEE&t=8s)

If you ever want to dig a little deeper into the ingredients or the clinical results, the full product details are on our site too: [M4 Face Cream Rx](https://www.myalloy.com/solutions/m4).


**M4 Face Cream Rx**

Estriol

Restore elasticity, hydrate deeply and build collagen—this powerful estriol-enriched face cream does it all

[Start Now](https://secure.myalloy.com/experience?categories%5B%5D=skin-health&sku-ids%5B%5D=d7fe4df5-7fd8-42c1-86d5-9be36bd6833c&skip-category-select=true&type=intake)

---

This answer was created using the following resources:

- [Get Back to Glowing with M4! - About Alloy M4 Cream](https://www.youtube.com/watch?v=ZM5sP8eCJEE)
- [M4 Feels Like Luxury, Works Like a Prescription!](https://www.youtube.com/watch?v=QPxXtmN1kfo)
- [Thank you so much Dr. Mary Claire Haver for sharing your updated routine! - Benefits of Alloys M4 Face Cream](https://www.youtube.com/watch?v=NvtVIfs8McQ)
- [Dr. Ellen Gendler on Why You Should Put Estrogen On Your Face](https://www.youtube.com/watch?v=Y1dwbvcJn08)
- [What’s the 🔑 to @AngieHotandFlashy’s science-backed evening skincare routine? M4! - Estrogen Cream Introduction](https://www.youtube.com/watch?v=o1I3Q6Jx6O4)
- [Use Alloy’s M4 in Your Skincare Routine](https://www.youtube.com/watch?v=cGWM7kDbbT8)
- [The Story Behind M4 from Alloy's Co-Founder Monica Molenaar](https://www.myalloy.com/blog/monicas-skincare-journey-from-discovery-to-results-the-story-behind-m4)
- [Skincare Routine | M4](https://www.myalloy.com/blog/why-estrogen-belongs-in-your-skincare-routine-and-not-just-in-your-hormone)

---

*This is a markdown version of [https://www.myalloy.com/knowledge-base/alloy-m4-cream-active-ingredient-and-concentration](https://www.myalloy.com/knowledge-base/alloy-m4-cream-active-ingredient-and-concentration) for AI/LLM consumption.*