---
title: "When the Rage is Real"
description: "Menopause rage and irritability often stem from estrogen and progesterone changes disrupting mood-regulating hormones; explore plant-based, FDA-approved therapies to restore balance and find relief."
url: "https://www.myalloy.com/blog/the-flash-simmer-down-now"
---

# When the Rage is Real 

By Rachel Baker

## Summary

**Perimenopause** and **menopause** can trigger intense emotional symptoms such as irritability and rage due to fluctuations in **estrogen** and **progesterone** levels, which disrupt brain chemicals like serotonin, dopamine, norepinephrine, and GABA. Plant-based, biodentical, FDA-approved hormone therapies—including creams, patches, and pills—offer options for restoring hormonal balance and alleviating mood disturbances for women experiencing these transitions.

[Find Your Plan](https://secure.myalloy.com/experience)

SPILLED COFFEE. *HATE.* ZOOM. *LOATHE. *The fact that no one will put their dishes in
the dishwasher. *Getting hot over here. *America’s maternal health crisis. *Inexcusable.* America’s prison crisis. *What the hell, people.* The death of *Rent *mastermind Jonathan Larson, at 35, as depicted in last year’s Lin-Manuel Miranda film *Tick, Tick…Boom!* starring Andrew Garfield. *Flat-out maddening.* The way that lady with the kohlrabi keeps looking at us at the farmer’s market.* She best cut it out if she wants to keep that cabbage.* The way the nation mourned back in 2019 when Bei Bei the panda’s mother, Mei Xiang, went into menopause at 21. *Our blood is at a rolling boil.*

WE COULD GO ON. INSTEAD, WE'LL pass the mic to menopausal muse Sharon Stone to distill what’s going on here: **“It’s kind of a hormonal shitshow.” **(We highly recommend Stone’s memoir.)

WHAT MOST OF US REFER TO AS RAGE —which if you’re reading this you know comes in flavors ranging from simmering to melt-your-face-off hot—Alloy’s Chief Medical Officer [Sharon Malone, M.D.,](https://www.myalloy.com/expert/dr-sharon-malone-md) FACOG, NCMP, more gently calls [irritability](https://www.myalloy.com/symptoms/irritability). Kinda flattering, right? We’ll take it. The scientific explanation for why we’re suddenly stripped of our chill points back to the estrogen and progesterone of it all. When those hormone levels dip, they set off a chain reaction that throws off the brain’s mood-balancing chemicals. With your “calming” GABA, “rewarding” dopamine, “energizing” norepinephrine, and “mood-boosting” serotonin out of whack, well, the rest of the world should gird their loins.

![Alloy Pouch and products on bathroom counter.](https://images.ctfassets.net/md0kv0ejg0xf/4ujGlJ88XL4y6CF1h9Fbd3/bc79c1ea550c169015ca76596b4d445a/Stocksy_txpb214ae1ftbK300_Medium_4118674-full-set-1-working-5.jpg)

IF THAT SOUNDS LIKE A GRIM FORECAST, **here’s an idea: Consider getting those hormones back into whack—or at least closer to their premenopause-era whack— **with Alloy’s easy-to-get-your-mitts-on therapies. [The products](https://www.myalloy.com/solutions), which are all plant- based, biodentical, and FDA-approved, come in creams, [patches](https://www.myalloy.com/solutions/estradiol-patch), and pills depending on your needs and preferences. To get started—or to even just learn more about us—take our [new online
assessment](https://dashboard.myalloy.com/get-started). We promise you this little exercise will incite no rage, and you never
know—the act of taking control of your own destiny may even provide you with an unexpected wave of zen.

Peace to you and yours,
**Alloy**

## Related Content

1. [https://www.myalloy.com/expert/dr-sharon-malone-md](https://www.myalloy.com/expert/dr-sharon-malone-md)
2. [https://www.myalloy.com/symptoms/irritability](https://www.myalloy.com/symptoms/irritability)
3. [https://www.myalloy.com/solutions](https://www.myalloy.com/solutions)
4. [https://www.myalloy.com/solutions/estradiol-patch](https://www.myalloy.com/solutions/estradiol-patch)

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*This is a markdown version of [https://www.myalloy.com/blog/the-flash-simmer-down-now](https://www.myalloy.com/blog/the-flash-simmer-down-now) for AI/LLM consumption.*